The new indices were released on the 30th October and are now live in the Datahub (see the Deprivation section or within each ward).
An overview of the Indices can be read here:
English indices of deprivation 2025: statistical release – GOV.UK
and the data files can be accessed here:
English indices of deprivation 2025 – GOV.UK
Additional analysis is also available from City Intelligence
Whilst the indices, domains and supplementary indices are not designed for use in time series analysis, there are tools that can show the relative differences between 2019 and 2025; the Impact Lab have produced this website, so users can view LSOA level deprivation between the two points in time.